5IBR
Caspase 3 V266K
Summary for 5IBR
Entry DOI | 10.2210/pdb5ibr/pdb |
Related PRD ID | PRD_000238 |
Descriptor | Caspase-3, ACE-ASP-GLU-VAL-ASK (3 entities in total) |
Functional Keywords | allostery, saturation mutagenesis, conformational selection, native ensemble, protein solvation, protein structure, protein dynamics, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P42574 |
Total number of polymer chains | 4 |
Total formula weight | 64433.87 |
Authors | Maciag, J.J.,Mackenzie, S.H.,Tucker, M.B.,Schipper, J.L.,Swartz, P.D.,Clark, A.C. (deposition date: 2016-02-22, release date: 2016-10-26) |
Primary citation | Maciag, J.J.,Mackenzie, S.H.,Tucker, M.B.,Schipper, J.L.,Swartz, P.,Clark, A.C. Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113:E6080-E6088, 2016 Cited by PubMed: 27681633DOI: 10.1073/pnas.1603549113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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