5IAY

NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide

Summary for 5IAY

• Entry DOI: 10.2210/pdb5iay/pdb
• NMR Information: BMRB: 30019
• Descriptor: E3 ubiquitin-protein ligase UHRF1, Spacer (2 entities in total)
• Functional Keywords: uhrf1, ttd, spacer, ligase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q96T88
• Total number of polymer chains: 2
• Total formula weight: 19411.72

Authors

Fang, J.,Cheng, J.,Wang, J.,Zhang, Q.,Liu, M.,Gong, R.,Wang, P.,Zhang, X.,Feng, Y.,Lan, W.,Gong, Z.,Tang, C.,Wong, J.,Yang, H.,Cao, C.,Xu, Y. (deposition date: 2016-02-22, release date: 2016-04-20)

• Primary citation: Fang, J.,Cheng, J.,Wang, J.,Zhang, Q.,Liu, M.,Gong, R.,Wang, P.,Zhang, X.,Feng, Y.,Lan, W.,Gong, Z.,Tang, C.,Wong, J.,Yang, H.,Cao, C.,Xu, Y.; Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition; Nat Commun, 7:11197-11197, 2016; PubMed: 27045799; DOI: 10.1038/ncomms11197

Experimental method

SOLUTION NMR