5IAK

Caspase 3 V266S

5IAK の概要

• エントリーDOI: 10.2210/pdb5iak/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000238
• 分子名称: Caspase-3, ACE-ASP-GLU-VAL-ASK, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: allostery, saturation mutagenesis, conformational selection, native ensemble, protein solvation, protein structure, protein dynamics, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm: P42574
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32310.98

構造登録者

Maciag, J.J.,Mackenzie, S.H.,Tucker, M.B.,Schipper, J.L.,Swartz, P.D.,Clark, A.C. (登録日: 2016-02-21, 公開日: 2016-10-26)

• 主引用文献: Maciag, J.J.,Mackenzie, S.H.,Tucker, M.B.,Schipper, J.L.,Swartz, P.,Clark, A.C.; Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection.; Proc.Natl.Acad.Sci.USA, 113:E6080-E6088, 2016; PubMed: 27681633; DOI: 10.1073/pnas.1603549113

実験手法

X-RAY DIFFRACTION (1.82 Å)