5HWC

Aspergillus fumigatus FKBP12 P90G protein bound with FK506 in P212121 space group

Summary for 5HWC

• Entry DOI: 10.2210/pdb5hwc/pdb
• Related: 5HWB
• Descriptor: FK506-binding protein 1A, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total)
• Functional Keywords: fkbp12, prolyl isomerase, fk506, isomerase
• Biological source: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
• Cellular location: Cytoplasm : Q4WLV6
• Total number of polymer chains: 1
• Total formula weight: 13189.93

Authors

Tonthat, N.K.,Schumacher, M.A. (deposition date: 2016-01-29, release date: 2016-09-14, Last modification date: 2024-03-06)

• Primary citation: Tonthat, N.K.,Juvvadi, P.R.,Zhang, H.,Lee, S.C.,Venters, R.,Spicer, L.,Steinbach, W.J.,Heitman, J.,Schumacher, M.A.; Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.; Mbio, 7:e00492-e00416, 2016; PubMed: 27118592; DOI: 10.1128/mBio.00492-16

Experimental method

X-RAY DIFFRACTION (2.05 Å)