5HV9
Human LTC4S mutant-S36E
Summary for 5HV9
Entry DOI | 10.2210/pdb5hv9/pdb |
Descriptor | Leukotriene C4 synthase, GLUTATHIONE, SULFATE ION (3 entities in total) |
Functional Keywords | ltc4s, mutant, lyase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus outer membrane; Multi-pass membrane protein: Q16873 |
Total number of polymer chains | 1 |
Total formula weight | 17856.97 |
Authors | Thulasingam, M.,Ahmad, H.R.S.,Rinaldo-Matthis, A.,Haeggstrom, J.Z. (deposition date: 2016-01-28, release date: 2016-07-13, Last modification date: 2024-01-10) |
Primary citation | Ahmad, S.,Ytterberg, A.J.,Thulasingam, M.,Tholander, F.,Bergman, T.,Zubarev, R.,Wetterholm, A.,Rinaldo-Matthis, A.,Haeggstrom, J.Z. Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity. J.Biol.Chem., 291:18410-18418, 2016 Cited by PubMed: 27365393DOI: 10.1074/jbc.M116.735647 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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