5HV9

Human LTC4S mutant-S36E

Summary for 5HV9

Entry DOI	10.2210/pdb5hv9/pdb
Descriptor	Leukotriene C4 synthase, GLUTATHIONE, SULFATE ION (3 entities in total)
Functional Keywords	ltc4s, mutant, lyase
Biological source	Homo sapiens (Human)
Cellular location	Nucleus outer membrane; Multi-pass membrane protein: Q16873
Total number of polymer chains	1
Total formula weight	17856.97
Authors	Thulasingam, M.,Ahmad, H.R.S.,Rinaldo-Matthis, A.,Haeggstrom, J.Z. (deposition date: 2016-01-28, release date: 2016-07-13, Last modification date: 2024-01-10)
Primary citation	Ahmad, S.,Ytterberg, A.J.,Thulasingam, M.,Tholander, F.,Bergman, T.,Zubarev, R.,Wetterholm, A.,Rinaldo-Matthis, A.,Haeggstrom, J.Z. Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity. J.Biol.Chem., 291:18410-18418, 2016 Cited by PubMed: 27365393 DOI: 10.1074/jbc.M116.735647 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation