5HV8

Solution structure of an octanoyl- loaded acyl carrier protein domain from module MLSA2 of the mycolactone polyketide synthase.

5HV8 の概要

• エントリーDOI: 10.2210/pdb5hv8/pdb
• NMR情報: BMRB: 30006
• 分子名称: Type I modular polyketide synthase, S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate (2 entities in total)
• 機能のキーワード: acyl carrier protein mycolactone, transferase
• 由来する生物種: Mycobacterium ulcerans; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10722.02

構造登録者

Vance, S.,Tkachenko, O.,Thomas, B.,Bassuni, M.,Hong, H.,Nietlispach, D.,Broadhurst, R.W. (登録日: 2016-01-28, 公開日: 2016-03-09, 最終更新日: 2019-10-23)

• 主引用文献: Vance, S.,Tkachenko, O.,Thomas, B.,Bassuni, M.,Hong, H.,Nietlispach, D.,Broadhurst, W.; Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase.; Biochem.J., 473:1097-1110, 2016; PubMed: 26920023; DOI: 10.1042/BCJ20160041

実験手法

SOLUTION NMR