5HN9

Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1186

Summary for 5HN9

Entry DOI	10.2210/pdb5hn9/pdb
Related	5HN7 5HN8 5HNA
Descriptor	Farnesyl pyrophosphate synthase, putative, 2-{[3-(decyloxy)benzyl]oxy}-5-nitrobenzoic acid (3 entities in total)
Functional Keywords	all helices, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Plasmodium vivax
Total number of polymer chains	4
Total formula weight	176854.78
Authors	Liu, Y.-L.,Zhang, Y.,OIdfield, E. (deposition date: 2016-01-18, release date: 2016-09-07, Last modification date: 2023-09-27)
Primary citation	G Ricci, C.,Liu, Y.L.,Zhang, Y.,Wang, Y.,Zhu, W.,Oldfield, E.,McCammon, J.A. Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55:5180-5190, 2016 Cited by PubMed: 27564465 DOI: 10.1021/acs.biochem.6b00398 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.12 Å)

Structure validation