5HLL

Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO.

Replaces:  4G4A

Summary for 5HLL

• Entry DOI: 10.2210/pdb5hll/pdb
• Descriptor: Lysozyme C, DIMETHYL SULFOXIDE, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: cisplatin, histidine, dmso, hen egg white lysozyme, raw diffraction images data, hydrolase
• Biological source: Gallus gallus (Chicken)
• Total number of polymer chains: 1
• Total formula weight: 15015.34

Authors

Helliwell, J.R. (deposition date: 2016-01-15, release date: 2016-03-02, Last modification date: 2024-11-06)

Primary citation

Tanley, S.W.,Schreurs, A.M.,Kroon-Batenburg, L.M.,Helliwell, J.R.
Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO.
Acta Crystallogr F Struct Biol Commun, 72:253-254, 2016

PubMed Abstract: A re-refinement of 4g4a, the room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO is published as an addendum to Tanley et al. [(2012), Acta Cryst. F68, 1300-1306]. This example illustrates the benefits of sharing raw diffraction images, as well as structure factors and molecular coordinates, as the diffraction resolution of the study is now much improved at 1.70 Å.

PubMed: 26948967
DOI: 10.1107/S2053230X16000856

Experimental method

X-RAY DIFFRACTION (1.7 Å)