5HIX

Cocrystal structure of an anti-parallel DNA G-quadruplex and a tetra-Quinoline Foldamer

5HIX の概要

分子名称Dimeric G-quadruplex, POTASSIUM ION, 4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-nitroquinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinoline-2-carboxylic acid, ... (4 entities in total)
機能のキーワードdna g-quadruplex, foldamer, foldamer-quadruplex, g-quadruplex ligands, dna
由来する生物種synthetic construct
ポリマー鎖数2
分子量合計8788.36
構造登録者
Mandal, P.K.,Baptiste, B.,Langlois d'Estaintot, B.,Kauffmann, B.,Huc, I. (登録日: 2016-01-12, 公開日: 2016-11-02)
主引用文献
Mandal, P.K.,Baptiste, B.,Langlois d'Estaintot, B.,Kauffmann, B.,Huc, I.
Multivalent Interactions between an Aromatic Helical Foldamer and a DNA G-Quadruplex in the Solid State.
Chembiochem, 17:1911-1914, 2016
PubMed: 27472456 (主引用文献が同じPDBエントリー)
DOI: 10.1002/cbic.201600281
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.48 Å)
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構造検証レポート

RfreeClashscoreRSRZ outliers0.285150MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 5hix
回転なし
Molmil generated image of 5hix
x軸(左右方向)周りに90°回転
Molmil generated image of 5hix
y軸(上下方向)周りに90°回転