5HIX

Cocrystal structure of an anti-parallel DNA G-quadruplex and a tetra-Quinoline Foldamer

5HIX の概要

• エントリーDOI: 10.2210/pdb5hix/pdb
• 分子名称: Dimeric G-quadruplex, POTASSIUM ION, 4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-({[4-(3-aminopropoxy)-8-nitroquinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinoline-2-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: dna g-quadruplex, foldamer, foldamer-quadruplex, g-quadruplex ligands, dna
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8788.35

構造登録者

Mandal, P.K.,Baptiste, B.,Langlois d'Estaintot, B.,Kauffmann, B.,Huc, I. (登録日: 2016-01-12, 公開日: 2016-11-02, 最終更新日: 2024-01-10)

• 主引用文献: Mandal, P.K.,Baptiste, B.,Langlois d'Estaintot, B.,Kauffmann, B.,Huc, I.; Multivalent Interactions between an Aromatic Helical Foldamer and a DNA G-Quadruplex in the Solid State.; Chembiochem, 17:1911-1914, 2016; PubMed: 27472456; DOI: 10.1002/cbic.201600281

実験手法

X-RAY DIFFRACTION (2.48 Å)