5H7V

Structure of full-length extracellular domain of HAI-1 at pH 4.6

Summary for 5H7V

• Entry DOI: 10.2210/pdb5h7v/pdb
• Descriptor: Kunitz-type protease inhibitor 1 (1 entity in total)
• Functional Keywords: hai-1, hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted: O43278
• Total number of polymer chains: 1
• Total formula weight: 47295.85

Authors

Liu, M.,Huang, M. (deposition date: 2016-11-21, release date: 2017-03-29, Last modification date: 2023-11-08)

• Primary citation: Liu, M.,Yuan, C.,Jensen, J.K.,Zhao, B.,Jiang, Y.,Jiang, L.,Huang, M.; The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition; J. Biol. Chem., 292:8412-8423, 2017; PubMed: 28348076; DOI: 10.1074/jbc.M117.779256

Experimental method

X-RAY DIFFRACTION (3.82 Å)