5H65
Crystal structure of human POT1 and TPP1
Summary for 5H65
Entry DOI | 10.2210/pdb5h65/pdb |
Descriptor | Protection of telomeres protein 1, Adrenocortical dysplasia protein homolog, ZINC ION, ... (4 entities in total) |
Functional Keywords | telomere, dna binding protein, ob fold |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9NUX5 Q96AP0 |
Total number of polymer chains | 2 |
Total formula weight | 38810.01 |
Authors | |
Primary citation | Chen, C.,Gu, P.,Wu, J.,Chen, X.,Niu, S.,Sun, H.,Wu, L.,Li, N.,Peng, J.,Shi, S.,Fan, C.,Huang, M.,Wong, C.C.,Gong, Q.,Kumar-Sinha, C.,Zhang, R.,Pusztai, L.,Rai, R.,Chang, S.,Lei, M. Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer. Nat Commun, 8:14929-14929, 2017 Cited by PubMed: 28393832DOI: 10.1038/ncomms14929 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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