5GWX
Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylmethionine and sarcosine
Summary for 5GWX
Entry DOI | 10.2210/pdb5gwx/pdb |
Descriptor | Glycine sarcosine N-methyltransferase, S-ADENOSYLMETHIONINE, SARCOSINE, ... (5 entities in total) |
Functional Keywords | s-adenosylmethionine-dependent methyltransferases, sam, adomet-mtase, class i monomethylation, glycine, sarcosine rate-limiting enzyme, betaine biosynthesis betaine-mediated feedback inhibition, transferase |
Biological source | Methanohalophilus portucalensis FDF-1 |
Total number of polymer chains | 1 |
Total formula weight | 33536.09 |
Authors | |
Primary citation | Lee, Y.R.,Lin, T.S.,Lai, S.J.,Liu, M.S.,Lai, M.C.,Chan, N.L. Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity. Sci Rep, 6:38071-38071, 2016 Cited by PubMed: 27934872DOI: 10.1038/srep38071 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.205 Å) |
Structure validation
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