5GWX

Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylmethionine and sarcosine

5GWX の概要

• エントリーDOI: 10.2210/pdb5gwx/pdb
• 分子名称: Glycine sarcosine N-methyltransferase, S-ADENOSYLMETHIONINE, SARCOSINE, ... (5 entities in total)
• 機能のキーワード: s-adenosylmethionine-dependent methyltransferases, sam, adomet-mtase, class i monomethylation, glycine, sarcosine rate-limiting enzyme, betaine biosynthesis betaine-mediated feedback inhibition, transferase
• 由来する生物種: Methanohalophilus portucalensis FDF-1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33536.09

構造登録者

Lee, Y.R.,Lin, T.S.,Lai, S.J.,Liu, M.S.,Lai, M.C.,Chan, N.L. (登録日: 2016-09-14, 公開日: 2016-11-23, 最終更新日: 2023-11-08)

• 主引用文献: Lee, Y.R.,Lin, T.S.,Lai, S.J.,Liu, M.S.,Lai, M.C.,Chan, N.L.; Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity.; Sci Rep, 6:38071-38071, 2016; PubMed: 27934872; DOI: 10.1038/srep38071

実験手法

X-RAY DIFFRACTION (2.205 Å)