5GV5

Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor

5GV5 の概要

• エントリーDOI: 10.2210/pdb5gv5/pdb
• 分子名称: Lipase B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: lipase, inhibitor, phosphonate, cal-b, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Pseudozyma antarctica
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 270940.08

構造登録者

Park, S.Y.,Lee, H. (登録日: 2016-09-02, 公開日: 2017-09-13, 最終更新日: 2020-07-29)

• 主引用文献: Park, K.,Kim, S.,Park, J.,Joe, S.,Min, B.,Oh, J.,Song, J.,Park, S.Y.,Park, S.,Lee, H.; Structural and Experimental Evidence for the Enantiomeric Recognition toward a Bulky sec-Alcohol by Candida antarctica Lipase B; Acs Catalysis, 6:7458-7465, 2016; DOI: 10.1021/acscatal.6b02192

実験手法

X-RAY DIFFRACTION (2.89 Å)