5GS0

Crystal structure of the complex of TLR3 and bi-specific diabody

Summary for 5GS0

• Entry DOI: 10.2210/pdb5gs0/pdb
• Related: 5GRU 5GRV 5GRW 5GRX 5GRY 5GRZ 5GS1 5GS2 5GS3
• Descriptor: Toll-like receptor 3, light chain (anti-TLR3), heavy chain (anti-TLR3), ... (8 entities in total)
• Functional Keywords: diabody, antibody fragment, complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 262271.39

Authors

Kim, J.H.,Song, D.H.,Youn, S.J.,Kim, J.W.,Cho, G.,Lee, H.,Lee, J.O. (deposition date: 2016-08-13, release date: 2016-10-12, Last modification date: 2024-03-20)

• Primary citation: Kim, J.H.,Song, D.H.,Youn, S.J.,Kim, J.W.,Cho, G.,Kim, S.C.,Lee, H.,Jin, M.S.,Lee, J.O.; Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.; Sci Rep, 6:34515-34515, 2016; PubMed: 27682821; DOI: 10.1038/srep34515

Experimental method

X-RAY DIFFRACTION (3.275 Å)