5GRG

Crystal structure of dual peptide from EBV in complex with HLA-A*11:01

Summary for 5GRG

Related5GRD
DescriptorHLA class I histocompatibility antigen, A-11 alpha chain, Beta-2-microglobulin, Epstein Barr Virus, Latent Membrane Protein 2 epitope, ... (6 entities in total)
Functional Keywordsimmune system, human leukocyte antigen
Biological sourceHomo sapiens (Human)
More
Cellular locationMembrane; Single-pass type I membrane protein P13746
Secreted . Note=(Microbial infection) In the presence of M P61769
Total number of polymer chains4
Total molecular weight44988.74
Authors
Tadwal, V.S.,Xiao, Z.,Ren, E.C. (deposition date: 2016-08-11, release date: 2017-08-09)
Primary citation
Xiao, Z.,Ye, Z.,Tadwal, V.S.,Shen, M.,Ren, E.C.
Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens
Sci Rep, 7:5072-5072, 2017
PubMed: 28698575 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-017-05171-w
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.94 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.247103.3%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution