5GRF
Crystal structure of the alpha gamma mutant (gamma-K151A) of human IDH3 in complex with Mg(2+), citrate and ADP
Summary for 5GRF
Entry DOI | 10.2210/pdb5grf/pdb |
Related | 5GRE 5GRH 5GRI 5GRL |
Descriptor | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, CITRIC ACID, ... (6 entities in total) |
Functional Keywords | k151a, mutant, allosteric regulation, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Cellular location | Mitochondrion: P50213 P51553 |
Total number of polymer chains | 2 |
Total formula weight | 76135.23 |
Authors | |
Primary citation | Ma, T.,Peng, Y.,Huang, W.,Ding, J. Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase. Sci Rep, 7:40921-40921, 2017 Cited by PubMed: 28098230DOI: 10.1038/srep40921 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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