5GO1

Structural, Functional characterization and discovery of novel inhibitors of Leishmania amazonensis Nucleoside Diphosphatase Kinase (NDK)

5GO1 の概要

• エントリーDOI: 10.2210/pdb5go1/pdb
• 分子名称: Nucleoside diphosphate kinase (2 entities in total)
• 機能のキーワード: kinase, leishmania amazonensis, inhibitor, transferase
• 由来する生物種: Leishmania amazonensis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16714.08

構造登録者

Mishra, A.K.,Agnihotri, P.,Singh, S.P.,Pratap, J.V. (登録日: 2016-07-26, 公開日: 2017-07-26, 最終更新日: 2023-11-08)

• 主引用文献: Mishra, A.K.,Singh, N.,Agnihotri, P.,Mishra, S.,Singh, S.P.,Kolli, B.K.,Chang, K.P.,Sahasrabuddhe, A.A.,Siddiqi, M.I.,Pratap, J.V.; Discovery of novel inhibitors for Leishmania nucleoside diphosphatase kinase (NDK) based on its structural and functional characterization.; J. Comput. Aided Mol. Des., 31:547-562, 2017; PubMed: 28551817; DOI: 10.1007/s10822-017-0022-9

実験手法

X-RAY DIFFRACTION (2.5 Å)