5GIS

Crystal structure of a Fab fragment with its ligand peptide

Summary for 5GIS

• Entry DOI: 10.2210/pdb5gis/pdb
• Related: 5GIR
• Descriptor: Heavy chain of Fab fragment, Light chain of Fab fragment, THR-LYS-PRO-ILE-THR-ILE-GLY-SER-HIS-ALA-HIS-GLY-ASP-GLN-TYR-LYS, ... (5 entities in total)
• Functional Keywords: fab, peptide ligand, mutation, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 53764.98

Authors

Kitago, Y.,Kaneko, K.K.,Ogasawara, S.,Kato, Y.,Takagi, J. (deposition date: 2016-06-24, release date: 2016-09-14, Last modification date: 2023-11-08)

• Primary citation: Kitago, Y.,Kaneko, M.K.,Ogasawara, S.,Kato, Y.,Takagi, J.; Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1.; Biochem. Biophys. Res. Commun., 478:1274-1279, 2016; PubMed: 27553275; DOI: 10.1016/j.bbrc.2016.08.110

Experimental method

X-RAY DIFFRACTION (1.93 Å)