5GHY
Crystal structure of beta-lactamase PenP mutant-E166H in complex with cephaloridine as "post-acylation" intermediate
Summary for 5GHY
Entry DOI | 10.2210/pdb5ghy/pdb |
Related | 5GHX 5GHZ |
Descriptor | Beta-lactamase, 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID (3 entities in total) |
Functional Keywords | hydrolase |
Biological source | Bacillus licheniformis |
Cellular location | Cell membrane ; Lipid-anchor : P00808 |
Total number of polymer chains | 2 |
Total formula weight | 60354.50 |
Authors | |
Primary citation | Pan, X.,He, Y.,Lei, J.,Huang, X.,Zhao, Y. Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis J. Biol. Chem., 292:4022-4033, 2017 Cited by PubMed: 28100776DOI: 10.1074/jbc.M116.764340 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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