5GG9

Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-GTP, 8-oxo-GMP and pyrophosphate

5GG9 の概要

• エントリーDOI: 10.2210/pdb5gg9/pdb
• 関連するPDBエントリー: 5GG5 5GG6 5GG7 5GG8 5GGA 5GGB 5GGC 5GGD
• 分子名称: Hydrolase, NUDIX family protein, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, [(2R,3S,4R,5R)-5-[2-azanyl-6,8-bis(oxidanylidene)-1,7-dihydropurin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, ... (6 entities in total)
• 機能のキーワード: 8-oxo-guanine nucleotides, sanitization of nucleotide pool, nudix enzyme, histidine phosphatase domain, binding sites at intermolecular interface, enzyme action, hydrolase
• 由来する生物種: Mycobacterium smegmatis str. MC2 155
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39271.81

構造登録者

Arif, S.M.,Patil, A.G.,Varshney, U.,Vijayan, M. (登録日: 2016-06-15, 公開日: 2017-04-19, 最終更新日: 2023-11-08)

• 主引用文献: Arif, S.M.,Patil, A.G.,Varshney, U.,Vijayan, M.; Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association; Acta Crystallogr D Struct Biol, 73:349-364, 2017; PubMed: 28375146; DOI: 10.1107/S2059798317002534

実験手法

X-RAY DIFFRACTION (1.6 Å)