5FYU

Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment 3-Amino-4-methyl-1,3-dihydro-2H-indol-2-one (N10042a)

5FYU の概要

• エントリーDOI: 10.2210/pdb5fyu/pdb
• 関連するPDBエントリー: 5FXV 5FXW 5FXX 5FXZ 5FY0 5FY1 5FY4 5FY5 5FY7 5FY8 5FY9 5FYB 5FYC 5FYH 5FYI 5FYM 5FYS 5FYT 5FYV 5FYY 5FYZ 5FZ0 5FZ1 5FZ3 5FZ4 5FZ6 5FZ7 5FZ8 5FZ9 5FZA 5FZB 5FZC 5FZD 5FZE 5FZF 5FZG 5FZH 5FZI 5FZK 5FZL 5FZM
• 分子名称: LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ... (9 entities in total)
• 機能のキーワード: oxidoreductase, jarid1b, plu1, pandda, fragment soaking, x-ray fragment screening, structural genomics consortium, sgc
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Nucleus : Q9UGL1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56723.48

構造登録者

Nowak, R.,Krojer, T.,Johansson, C.,Pearce, N.,Gileadi, C.,Kupinska, K.,Strain-Damerell, C.,Szykowska, A.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,von Delft, F.,Brennan, P.E.,Oppermann, U. (登録日: 2016-03-09, 公開日: 2016-03-23, 最終更新日: 2024-10-16)

• 主引用文献: Nowak, R.,Krojer, T.,Johansson, C.,Gileadi, C.,Kupinska, K.,Strain-Damerell, C.,Szykowska, A.,von Delft, F.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Oppermann, U.; Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with N10042A; To be Published,

実験手法

X-RAY DIFFRACTION (2.06 Å)