5FWK
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
Summary for 5FWK
Entry DOI | 10.2210/pdb5fwk/pdb |
Related | 5FWL 5FWM 5FWP |
EMDB information | 3337 |
Descriptor | HEAT SHOCK PROTEIN HSP 90 BETA, HSP90 CO-CHAPERONE CDC37, CYCLIN-DEPENDENT KINASE 4, ... (5 entities in total) |
Functional Keywords | signaling protein, hsp90, cdc37, cdk4, chaperone, kinase, unfolding |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 247497.04 |
Authors | Verba, K.A.,Wang, R.Y.R.,Arakawa, A.,Liu, Y.,Yokoyama, S.,Agard, D.A. (deposition date: 2016-02-17, release date: 2016-07-06, Last modification date: 2019-08-21) |
Primary citation | Verba, K.A.,Wang, R.Y.,Arakawa, A.,Liu, Y.,Shirouzu, M.,Yokoyama, S.,Agard, D.A. Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352:1542-, 2016 Cited by PubMed: 27339980DOI: 10.1126/SCIENCE.AAF5023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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