5FT2

Sub-tomogram averaging of Lassa virus glycoprotein spike from virus- like particles at pH 5

Summary for 5FT2

• Entry DOI: 10.2210/pdb5ft2/pdb
• EMDB information: 3292
• Descriptor: PRE-GLYCOPROTEIN POLYPROTEIN GP COMPLEX, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: cell adhesion, membrane protein, glycoprotein, receptor binding, membrane fusion
• Biological source: LASSA VIRUS (LASSA MAMMARENAVIRUS, LASV)
• Cellular location: Stable signal peptide: Virion membrane ; Multi-pass membrane protein . Glycoprotein G2: Virion membrane ; Single-pass membrane protein : P08669
• Total number of polymer chains: 1
• Total formula weight: 20670.91

Authors

Li, S.,Zhaoyang, S.,Pryce, R.,Parsy, M.L.,Fehling, S.K.,Schlie, K.,Siebert, C.A.,Garten, W.,Bowden, T.A.,Strecker, T.,Huiskonen, J.T. (deposition date: 2016-01-09, release date: 2016-03-02, Last modification date: 2020-07-29)

• Primary citation: Li, S.,Sun, Z.,Pryce, R.,Parsy, M.,Fehling, S.K.,Schlie, K.,Siebert, C.A.,Garten, W.,Bowden, T.A.,Strecker, T.,Huiskonen, J.T.; Acidic Ph-Induced Conformations and Lamp1 Binding of the Lassa Virus Glycoprotein Spike.; Plos Pathog., 12:5418-, 2016; PubMed: 26849049; DOI: 10.1371/JOURNAL.PPAT.1005418

Experimental method

ELECTRON MICROSCOPY (16.4 Å)