5FT2

Sub-tomogram averaging of Lassa virus glycoprotein spike from virus- like particles at pH 5

5FT2 の概要

• エントリーDOI: 10.2210/pdb5ft2/pdb
• EMDBエントリー: 3292
• 分子名称: PRE-GLYCOPROTEIN POLYPROTEIN GP COMPLEX, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: cell adhesion, membrane protein, glycoprotein, receptor binding, membrane fusion
• 由来する生物種: LASSA VIRUS (LASSA MAMMARENAVIRUS, LASV)
• 細胞内の位置: Stable signal peptide: Virion membrane ; Multi-pass membrane protein . Glycoprotein G2: Virion membrane ; Single-pass membrane protein : P08669
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20670.91

構造登録者

Li, S.,Zhaoyang, S.,Pryce, R.,Parsy, M.L.,Fehling, S.K.,Schlie, K.,Siebert, C.A.,Garten, W.,Bowden, T.A.,Strecker, T.,Huiskonen, J.T. (登録日: 2016-01-09, 公開日: 2016-03-02, 最終更新日: 2020-07-29)

• 主引用文献: Li, S.,Sun, Z.,Pryce, R.,Parsy, M.,Fehling, S.K.,Schlie, K.,Siebert, C.A.,Garten, W.,Bowden, T.A.,Strecker, T.,Huiskonen, J.T.; Acidic Ph-Induced Conformations and Lamp1 Binding of the Lassa Virus Glycoprotein Spike.; Plos Pathog., 12:5418-, 2016; PubMed: 26849049; DOI: 10.1371/JOURNAL.PPAT.1005418

実験手法

ELECTRON MICROSCOPY (16.4 Å)