5FSY

Crystal structure of Trypanosoma brucei macrodomain in complex with ADP-ribose

Summary for 5FSY

Entry DOI	10.2210/pdb5fsy/pdb
Related	5FSU 5FSV 5FSX 5FSZ
Descriptor	MACRODOMAIN, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total)
Functional Keywords	macrodomain, hydrolase, adp-ribose binding
Biological source	TRYPANOSOMA BRUCEI
Total number of polymer chains	1
Total formula weight	29734.87
Authors	Haikarainen, T.,Lehtio, L. (deposition date: 2016-01-08, release date: 2016-04-20, Last modification date: 2024-01-10)
Primary citation	Haikarainen, T.,Lehtio, L. Proximal Adp-Ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain. Sci.Rep., 6:24213-, 2016 Cited by PubMed: 27064071 DOI: 10.1038/SREP24213 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation