5FQC

Crystal structure of the metallo-beta-lactamase VIM-2 with 2C

Summary for 5FQC

• Entry DOI: 10.2210/pdb5fqc/pdb
• Related: 5FQ9
• Descriptor: BETA-LACTAMASE, FORMIC ACID, ZINC ION, ... (6 entities in total)
• Functional Keywords: hydrolase, antibiotic resistance
• Biological source: PSEUDOMONAS AERUGINOSA
• Total number of polymer chains: 2
• Total formula weight: 52755.96

Authors

Brem, J.,Cain, R.,McDonough, M.A.,Clifton, I.J.,Fishwick, C.W.G.,Schofield, C.J. (deposition date: 2015-12-08, release date: 2016-08-17, Last modification date: 2024-01-10)

• Primary citation: Brem, J.,Cain, R.,Cahill, S.,McDonough, M.A.,Clifton, I.J.,Jimenez-Castellanos, J.C.,Avison, M.B.,Spencer, J.,Fishwick, C.W.,Schofield, C.J.; Structural basis of metallo-beta-lactamase, serine-beta-lactamase and penicillin-binding protein inhibition by cyclic boronates.; Nat Commun, 7:12406-12406, 2016; PubMed: 27499424; DOI: 10.1038/ncomms12406

Experimental method

X-RAY DIFFRACTION (1.449 Å)