5FNX

Crystal structure at pH 9.0 of a potato STI-Kunitz bi-functional inhibitor of serine and aspartic proteases in space group p4322 and ph 9.0

5FNX の概要

• エントリーDOI: 10.2210/pdb5fnx/pdb
• 関連するPDBエントリー: 5FNW
• 分子名称: POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D (2 entities in total)
• 機能のキーワード: hydrolase, sti-kunitz inhibitor, aspartic proteases, serine proteases, protease inhibitor, bi-functional protease inhibitor, hydrolase inhibitor, kunitz-type inhibitor
• 由来する生物種: SOLANUM TUBEROSUM (POTATO)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20527.56

構造登録者

Guerra, Y.,Rudino-Pinera, E. (登録日: 2015-11-16, 公開日: 2016-07-06, 最終更新日: 2024-01-10)

• 主引用文献: Guerra, Y.,Valiente, P.A.,Pons, T.,Berry, C.,Rudino-Pinera, E.; Structures of a bi-functional Kunitz-type STI family inhibitor of serine and aspartic proteases: Could the aspartic protease inhibition have evolved from a canonical serine protease-binding loop?; J. Struct. Biol., 195:259-271, 2016; PubMed: 27329566; DOI: 10.1016/j.jsb.2016.06.014

実験手法

X-RAY DIFFRACTION (2.65 Å)