5FN4
Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble
Summary for 5FN4
Entry DOI | 10.2210/pdb5fn4/pdb |
Related | 5FN2 5FN3 5FN5 |
EMDB information | 3239 |
Descriptor | Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 174048.04 |
Authors | Bai, X.C.,Rajendra, E.,Yang, G.H.,Shi, Y.G.,Scheres, S.H.W. (deposition date: 2015-11-10, release date: 2015-12-16, Last modification date: 2019-09-11) |
Primary citation | Bai, X.C.,Rajendra, E.,Yang, G.,Shi, Y.,Scheres, S.H. Sampling the conformational space of the catalytic subunit of human gamma-secretase. Elife, 4:-, 2015 Cited by PubMed: 26623517DOI: 10.7554/eLife.11182 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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