5FGN

Integral membrane protein lipooligosaccharide phosphoethanolamine transferase A (EptA) from Neisseria meningitidis

5FGN の概要

• エントリーDOI: 10.2210/pdb5fgn/pdb
• 関連するPDBエントリー: 4KAV 4KAY
• 分子名称: lipooligosaccharide phosphoethanolamine transferase A, 2-O-octyl-beta-D-glucopyranose, DODECYL-BETA-D-MALTOSIDE, ... (5 entities in total)
• 機能のキーワード: endotoxin biosynthesis, epta, membrane protein, phosphoethanolamine transferase, polymixin resistance, hydrolase, phosphotransferase, transferase
• 由来する生物種: Neisseria meningitidis serogroup B
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63160.66

構造登録者

Anandan, A.,Vrielink, A. (登録日: 2015-12-21, 公開日: 2017-02-15, 最終更新日: 2023-09-27)

• 主引用文献: Anandan, A.,Evans, G.L.,Condic-Jurkic, K.,O'Mara, M.L.,John, C.M.,Phillips, N.J.,Jarvis, G.A.,Wills, S.S.,Stubbs, K.A.,Moraes, I.,Kahler, C.M.,Vrielink, A.; Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding.; Proc. Natl. Acad. Sci. U.S.A., 114:2218-2223, 2017; PubMed: 28193899; DOI: 10.1073/pnas.1612927114

実験手法

X-RAY DIFFRACTION (2.75 Å)