5FDD
Endonuclease inhibitor 1 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0
Summary for 5FDD
| Entry DOI | 10.2210/pdb5fdd/pdb |
| Related | 4ZHZ 5FDE 5FDG |
| Descriptor | Polymerase acidic protein,Polymerase acidic protein, 5-(2-chlorobenzyl)-2-hydroxy-3-nitrobenzaldehyde, MANGANESE (II) ION, ... (5 entities in total) |
| Functional Keywords | hydrolase/inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Influenza A virus More |
| Total number of polymer chains | 1 |
| Total formula weight | 22743.18 |
| Authors | Fudo, S.,Yamamoto, N.,Nukaga, M.,Odagiri, T.,Tashiro, M.,Hoshino, T. (deposition date: 2015-12-16, release date: 2015-12-30, Last modification date: 2023-11-08) |
| Primary citation | Fudo, S.,Yamamoto, N.,Nukaga, M.,Odagiri, T.,Tashiro, M.,Hoshino, T. Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit Biochemistry, 55:2646-2660, 2016 Cited by PubMed: 27088785DOI: 10.1021/acs.biochem.5b01087 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.506 Å) |
Structure validation
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