5FA6

wild type human CYPOR

Summary for 5FA6

• Entry DOI: 10.2210/pdb5fa6/pdb
• Related: 3QE2
• Descriptor: NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: cypor, cytochrome p450 reductase, flavoprotein, abs-like phenotype, oxidoreductase
• Biological source: Homo sapiens (Human)
• Cellular location: Endoplasmic reticulum membrane ; Single-pass membrane protein ; Cytoplasmic side : P16435
• Total number of polymer chains: 2
• Total formula weight: 144142.35

Authors

Xia, C.,Marohnic, C.,Panda, S.,Masters, B.S.,Kim, J.J.K. (deposition date: 2015-12-11, release date: 2016-08-17, Last modification date: 2024-03-06)

• Primary citation: McCammon, K.M.,Panda, S.P.,Xia, C.,Kim, J.J.,Moutinho, D.,Kranendonk, M.,Auchus, R.J.,Lafer, E.M.,Ghosh, D.,Martasek, P.,Kar, R.,Masters, B.S.,Roman, L.J.; Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.; J.Biol.Chem., 291:20487-20502, 2016; PubMed: 27496950; DOI: 10.1074/jbc.M116.716019

Experimental method

X-RAY DIFFRACTION (2.3 Å)