5EXH
Crystal structure of mTET3-CXXC domain in complex with 5-carboxylcytosine DNA at 1.3 Angstroms resolution.
Summary for 5EXH
Entry DOI | 10.2210/pdb5exh/pdb |
Descriptor | DNA (5'-D(*GP*AP*AP*TP*CP*(1CC)P*GP*GP*AP*TP*TP*C)-3'), Methylcytosine dioxygenase TET3, ZINC ION, ... (4 entities in total) |
Functional Keywords | mouse tet3, complex, 5-carboxylcytosine, reader, oxidoreductase-dna complex, oxidoreductase/dna |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 13045.29 |
Authors | Song, J. (deposition date: 2015-11-23, release date: 2016-02-03, Last modification date: 2023-09-27) |
Primary citation | Jin, S.G.,Zhang, Z.M.,Dunwell, T.L.,Harter, M.R.,Wu, X.,Johnson, J.,Li, Z.,Liu, J.,Szabo, P.E.,Lu, Q.,Xu, G.L.,Song, J.,Pfeifer, G.P. Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration. Cell Rep, 14:493-505, 2016 Cited by PubMed: 26774490DOI: 10.1016/j.celrep.2015.12.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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