5ES8

Crystal structure of the initiation module of LgrA in the thiolation state

Summary for 5ES8

Entry DOI	10.2210/pdb5es8/pdb
Related	5ES5 5ES6 5ES7 5ES9
Descriptor	Linear gramicidin synthetase subunit A, [(3~{R})-4-[[3-[2-[[(2~{S})-2-azanyl-3-methyl-butanoyl]amino]ethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] dihydrogen phosphate (3 entities in total)
Functional Keywords	nrps, formylation domain, adenylation domain, peptidyl carrier protein, ligase
Biological source	Brevibacillus parabrevis
Total number of polymer chains	2
Total formula weight	177007.22
Authors	Reimer, J.M.,Aloise, M.N.,Schmeing, T.M. (deposition date: 2015-11-16, release date: 2016-01-20, Last modification date: 2023-09-27)
Primary citation	Reimer, J.M.,Aloise, M.N.,Harrison, P.M.,Schmeing, T.M. Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase. Nature, 529:239-242, 2016 Cited by PubMed: 26762462 DOI: 10.1038/nature16503 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.547 Å)

Structure validation