5ER2

High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor. the analysis of the inhibitor binding and description of the rigid body shift in the enzyme

5ER2 の概要

• エントリーDOI: 10.2210/pdb5er2/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000262
• 分子名称: ENDOTHIAPEPSIN, 6-ammonio-N-{[(2R,3R)-3-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-4-cyclohexyl-2-hydroxybutyl](2-methylpropyl)carbamoyl}-L-norleucyl-L-phenylalanine (3 entities in total)
• 機能のキーワード: acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Cryphonectria parasitica (chestnut blight fungus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34762.06

構造登録者

Sali, A.,Veerapandian, B.,Cooper, J.B.,Foundling, S.I.,Hoover, D.J.,Blundell, T.L. (登録日: 1991-01-02, 公開日: 1991-04-15, 最終更新日: 2017-11-29)

• 主引用文献: Sali, A.,Veerapandian, B.,Cooper, J.B.,Foundling, S.I.,Hoover, D.J.,Blundell, T.L.; High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.; EMBO J., 8:2179-2188, 1989; PubMed: 2676515

実験手法

X-RAY DIFFRACTION (1.8 Å)