5ER1

A rational approach to the design of antihypertensives. X-ray studies of complexes between aspartic proteinases and aminoalcohol renin inhibitors

5ER1 の概要

• エントリーDOI: 10.2210/pdb5er1/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000308
• 分子名称: ENDOTHIAPEPSIN, methyl N-[(2S,3S)-3-amino-2-hydroxy-5-methylhexyl]-L-valyl-L-isoleucyl-L-phenylalaninate (3 entities in total)
• 機能のキーワード: acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Cryphonectria parasitica (chestnut blight fungus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34334.56

構造登録者

Cooper, J.B.,Foundling, S.I.,Blundell, T.L. (登録日: 1990-11-07, 公開日: 1991-01-15, 最終更新日: 2017-11-29)

• 主引用文献: Cooper, J.B.,Foundling, S.I.,Blundell, T.L.,Arrowsmith, R.J.,Harris, C.J.,Champness, J.N.; A Rational Approach to the Design of Antihypertensives. X-Ray Studies of Complexes between Aspartic Proteinases and Aminoalcohol Renin Inhibitors; Topics in Medicinal Chemistry, :308-, 1988

実験手法

X-RAY DIFFRACTION (2 Å)