5EQ0
Crystal Structure of chromodomain of CBX8 in complex with inhibitor UNC3866
Summary for 5EQ0
Entry DOI | 10.2210/pdb5eq0/pdb |
Related | 5ebj |
Related PRD ID | PRD_002208 |
Descriptor | Chromobox protein homolog 8, unc3866, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 7462.67 |
Authors | Liu, Y.,Tempel, W.,Walker, J.R.,Stuckey, J.I.,Dickson, B.M.,James, L.I.,Frye, S.V.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2015-11-12, release date: 2015-12-23, Last modification date: 2019-11-27) |
Primary citation | Stuckey, J.I.,Dickson, B.M.,Cheng, N.,Liu, Y.,Norris, J.L.,Cholensky, S.H.,Tempel, W.,Qin, S.,Huber, K.G.,Sagum, C.,Black, K.,Li, F.,Huang, X.P.,Roth, B.L.,Baughman, B.M.,Senisterra, G.,Pattenden, S.G.,Vedadi, M.,Brown, P.J.,Bedford, M.T.,Min, J.,Arrowsmith, C.H.,James, L.I.,Frye, S.V. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat.Chem.Biol., 12:180-187, 2016 Cited by PubMed: 26807715DOI: 10.1038/nchembio.2007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.18 Å) |
Structure validation
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