5EN5
Apo structure of bacterial efflux pump.
Summary for 5EN5
| Entry DOI | 10.2210/pdb5en5/pdb |
| Descriptor | Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB, DARPin (3 entities in total) |
| Functional Keywords | efflux pump, transport protein |
| Biological source | Escherichia coli (strain K12) More |
| Cellular location | Cell inner membrane ; Multi- pass membrane protein : P31224 |
| Total number of polymer chains | 6 |
| Total formula weight | 252174.67 |
| Authors | Sjuts, H.,Ornik, A.R.,Pos, K.M. (deposition date: 2015-11-09, release date: 2016-04-06, Last modification date: 2024-01-10) |
| Primary citation | Sjuts, H.,Vargiu, A.V.,Kwasny, S.M.,Nguyen, S.T.,Kim, H.S.,Ding, X.,Ornik, A.R.,Ruggerone, P.,Bowlin, T.L.,Nikaido, H.,Pos, K.M.,Opperman, T.J. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113:3509-3514, 2016 Cited by PubMed: 26976576DOI: 10.1073/pnas.1602472113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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