5ELW
A. thaliana IGPD2 in complex with the triazole-phosphonate inhibitor, (R)-C348, to 1.36A resolution
Summary for 5ELW
Entry DOI | 10.2210/pdb5elw/pdb |
Descriptor | Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid, ... (7 entities in total) |
Functional Keywords | herbicide development, histidine biosynthesis, inhibitor complex, dehydratase, lyase |
Biological source | Arabidopsis thaliana (Mouse-ear cress) |
Cellular location | Plastid, chloroplast : O23346 |
Total number of polymer chains | 1 |
Total formula weight | 22989.86 |
Authors | Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W. (deposition date: 2015-11-05, release date: 2016-10-05, Last modification date: 2024-01-10) |
Primary citation | Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W. Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide. Angew.Chem.Int.Ed.Engl., 55:13485-13489, 2016 Cited by PubMed: 27717128DOI: 10.1002/anie.201607185 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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