5ELW

A. thaliana IGPD2 in complex with the triazole-phosphonate inhibitor, (R)-C348, to 1.36A resolution

5ELW の概要

• エントリーDOI: 10.2210/pdb5elw/pdb
• 分子名称: Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid, ... (7 entities in total)
• 機能のキーワード: herbicide development, histidine biosynthesis, inhibitor complex, dehydratase, lyase
• 由来する生物種: Arabidopsis thaliana (Mouse-ear cress)
• 細胞内の位置: Plastid, chloroplast : O23346
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22989.86

構造登録者

Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W. (登録日: 2015-11-05, 公開日: 2016-10-05, 最終更新日: 2024-01-10)

• 主引用文献: Bisson, C.,Britton, K.L.,Sedelnikova, S.E.,Rodgers, H.F.,Eadsforth, T.C.,Viner, R.C.,Hawkes, T.R.,Baker, P.J.,Rice, D.W.; Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.; Angew.Chem.Int.Ed.Engl., 55:13485-13489, 2016; PubMed: 27717128; DOI: 10.1002/anie.201607185

実験手法

X-RAY DIFFRACTION (1.4 Å)