5EIE

mAChE-TZ2 complex

5EIE の概要

• エントリーDOI: 10.2210/pdb5eie/pdb
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: acetylcholinesterase, inhibitor, click chemistry, tacrine, hydrolase
• 由来する生物種: Mus musculus (House Mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 122224.25

構造登録者

Bourne, Y.,Marchot, P. (登録日: 2015-10-29, 公開日: 2016-01-20, 最終更新日: 2024-01-10)

• 主引用文献: Bourne, Y.,Sharpless, K.B.,Taylor, P.,Marchot, P.; Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase.; J.Am.Chem.Soc., 138:1611-1621, 2016; PubMed: 26731630; DOI: 10.1021/jacs.5b11384

実験手法

X-RAY DIFFRACTION (2.1 Å)