5EDC

human FABP4 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid at 1.29A

5EDC の概要

• エントリーDOI: 10.2210/pdb5edc/pdb
• 分子名称: Fatty acid-binding protein, adipocyte, 6-chloranyl-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: P15090
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15466.01

構造登録者

Rudolph, M.G.,Ehler, A. (登録日: 2015-10-21, 公開日: 2016-03-09, 最終更新日: 2024-05-08)

• 主引用文献: Kuhn, B.,Guba, W.,Hert, J.,Banner, D.,Bissantz, C.,Ceccarelli, S.,Haap, W.,Korner, M.,Kuglstatter, A.,Lerner, C.,Mattei, P.,Neidhart, W.,Pinard, E.,Rudolph, M.G.,Schulz-Gasch, T.,Woltering, T.,Stahl, M.; A Real-World Perspective on Molecular Design.; J.Med.Chem., 59:4087-4102, 2016; PubMed: 26878596; DOI: 10.1021/acs.jmedchem.5b01875

実験手法

X-RAY DIFFRACTION (1.29 Å)