5DYX

Crystal Structure of BAZ2B bromodomain in complex with fragment F59

Summary for 5DYX

Entry DOI	10.2210/pdb5dyx/pdb
Related	5DYU
Descriptor	Bromodomain adjacent to zinc finger domain protein 2B, ADENINE (3 entities in total)
Functional Keywords	four helical bundle, transcription
Biological source	Homo sapiens (Human)
Cellular location	Nucleus : Q9UIF8
Total number of polymer chains	1
Total formula weight	13666.70
Authors	Lolli, G.,Caflisch, A. (deposition date: 2015-09-25, release date: 2016-03-16, Last modification date: 2024-01-10)
Primary citation	Lolli, G.,Caflisch, A. High-Throughput Fragment Docking into the BAZ2B Bromodomain: Efficient in Silico Screening for X-Ray Crystallography. Acs Chem.Biol., 11:800-807, 2016 Cited by PubMed: 26942307 DOI: 10.1021/acschembio.5b00914 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation