5DYL

Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium Vivax - Apo form

Replaces:  4MYI

Summary for 5DYL

Related4MYI
DescriptorcGMP-dependent protein kinase, putative (2 entities in total)
Functional Keywordstransferase, kinase, structural genomics, structural genomics consortium, sgc
Biological sourcePlasmodium vivax
Total number of polymer chains1
Total molecular weight96726.65
Authors
Primary citation
El Bakkouri, M.,Kouidmi, I.,Wernimont, A.K.,Amani, M.,Hutchinson, A.,Loppnau, P.,Kim, J.J.,Flueck, C.,Walker, J.R.,Seitova, A.,Senisterra, G.,Kakihara, Y.,Kim, C.,Blackman, M.J.,Calmettes, C.,Baker, D.A.,Hui, R.
Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.
Proc.Natl.Acad.Sci.USA, 116:14164-14173, 2019
PubMed: 31239348 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1905558116
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2491 0.1% 0.9% 4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report