5DVP
Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with Doripenem adduct
Summary for 5DVP
Entry DOI | 10.2210/pdb5dvp/pdb |
Related | 5DU7 5DUJ 5DVQ |
Descriptor | L,D-transpeptidase 2, (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | peptidoglycan synthesis enzyme, cell wall enzyme, transferase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cell membrane ; Lipid-anchor : I6Y9J2 |
Total number of polymer chains | 2 |
Total formula weight | 76178.38 |
Authors | Kumar, P.,Lamichhane, G. (deposition date: 2015-09-21, release date: 2016-09-28, Last modification date: 2023-09-27) |
Primary citation | Kumar, P.,Kaushik, A.,Lloyd, E.P.,Li, S.G.,Mattoo, R.,Ammerman, N.C.,Bell, D.T.,Perryman, A.L.,Zandi, T.A.,Ekins, S.,Ginell, S.L.,Townsend, C.A.,Freundlich, J.S.,Lamichhane, G. Non-classical transpeptidases yield insight into new antibacterials. Nat. Chem. Biol., 13:54-61, 2017 Cited by PubMed: 27820797DOI: 10.1038/nchembio.2237 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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