5DVA

Fragments bound to the OXA-48 beta-lactamase: Compound 1

Summary for 5DVA

• Entry DOI: 10.2210/pdb5dva/pdb
• Related: 4s2p
• Descriptor: Beta-lactamase, 3-(pyridin-4-yl)benzoic acid, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: hydrolase, inhibitor, complex, fragment, lactamase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 4
• Total formula weight: 114059.84

Authors

Lund, B.A.,Christopeit, T.,Leiros, H.-K.S. (deposition date: 2015-09-21, release date: 2016-06-01, Last modification date: 2024-01-10)

• Primary citation: Lund, B.A.,Christopeit, T.,Guttormsen, Y.,Bayer, A.,Leiros, H.K.; Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening.; J.Med.Chem., 59:5542-5554, 2016; PubMed: 27165692; DOI: 10.1021/acs.jmedchem.6b00660

Experimental method

X-RAY DIFFRACTION (2.50003891197 Å)