5DUS

Crystal structure of MERS-CoV macro domain in complex with ADP-ribose

Summary for 5DUS

Entry DOI	10.2210/pdb5dus/pdb
Descriptor	ORF1a, ADENOSINE-5-DIPHOSPHORIBOSE, SULFATE ION, ... (5 entities in total)
Functional Keywords	ligand, complex, macro domain, adp-ribose, viral protein
Biological source	Middle East respiratory syndrome coronavirus
Cellular location	Host membrane ; Multi-pass membrane protein : T2B9G2
Total number of polymer chains	1
Total formula weight	18805.28
Authors	Cho, C.-C.,Lin, M.-H.,Chuang, C.-Y.,Hsu, C.-H. (deposition date: 2015-09-20, release date: 2016-01-13, Last modification date: 2024-03-20)
Primary citation	Cho, C.-C.,Lin, M.-H.,Chuang, C.-Y.,Hsu, C.-H. Macro Domain from Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Is an Efficient ADP-ribose Binding Module: CRYSTAL STRUCTURE AND BIOCHEMICAL STUDIES J.Biol.Chem., 291:4894-4902, 2016 Cited by PubMed: 26740631 DOI: 10.1074/jbc.M115.700542 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.432 Å)

Structure validation