5DUQ
Active human c1-inhibitor in complex with dextran sulfate
Summary for 5DUQ
Entry DOI | 10.2210/pdb5duq/pdb |
Related | 5DU3 |
Related PRD ID | PRD_900023 |
Descriptor | Plasma protease C1 inhibitor, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | serine protein inhibitor, complex with glycosaminoglycan, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P05155 |
Total number of polymer chains | 2 |
Total formula weight | 86871.75 |
Authors | Dijk, M.,Holkers, J.,Voskamp, P.,Giannetti, B.M.,Waterreus, W.J.,van Veen, H.A.,Pannu, N.S. (deposition date: 2015-09-20, release date: 2016-08-31, Last modification date: 2020-07-29) |
Primary citation | Dijk, M.,Holkers, J.,Voskamp, P.,Giannetti, B.M.,Waterreus, W.J.,van Veen, H.A.,Pannu, N.S. How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation. Structure, 24:2182-2189, 2016 Cited by PubMed: 27818099DOI: 10.1016/j.str.2016.09.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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