5DPX
1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases.
Summary for 5DPX
Entry DOI | 10.2210/pdb5dpx/pdb |
Related | 2FM6 2FU7 2FU8 2FU9 2GFJ 2GFK 2HB9 |
Descriptor | Metallo-beta-lactamase L1 type 3, ZINC ION, 5-(2-methylphenyl)-3H-1,2,4-triazole-3-thione, ... (5 entities in total) |
Functional Keywords | hydrolase, metallo, zn, lactamase |
Biological source | Stenotrophomonas maltophilia (Pseudomonas maltophilia) |
Cellular location | Periplasm : P52700 |
Total number of polymer chains | 2 |
Total formula weight | 58505.27 |
Authors | Nauton, L.,Garau, G.,Khan, R.,Dideberg, O. (deposition date: 2015-09-14, release date: 2017-01-11, Last modification date: 2024-01-10) |
Primary citation | Sevaille, L.,Gavara, L.,Bebrone, C.,De Luca, F.,Nauton, L.,Achard, M.,Mercuri, P.,Tanfoni, S.,Borgianni, L.,Guyon, C.,Lonjon, P.,Turan-Zitouni, G.,Dzieciolowski, J.,Becker, K.,Benard, L.,Condon, C.,Maillard, L.,Martinez, J.,Frere, J.M.,Dideberg, O.,Galleni, M.,Docquier, J.D.,Hernandez, J.F. 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases. ChemMedChem, 12:972-985, 2017 Cited by PubMed: 28505394DOI: 10.1002/cmdc.201700186 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report